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Hypersensitivity reactions have actually been reported in up to 10 % of individuals and have actually consisted of anaphylaxis, urticarial breakout, erythematous maculopapular breakout, lotion sickness-like responses, erythema multiforme, urticaria, edema, hypotension, high temperature, eosinophilia, exfoliative dermatitis, dangerous skin necrolysis, severe generalized exanthematous pustulosis, irritation vasculitis, angioedema, Stevens-Johnson disorder, and also dyspnea.